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dc.contributor.authorUamporn Siripanyaphinyoen_US
dc.contributor.authorDusit Laohasinnarongen_US
dc.contributor.authorJuthamas Siripaneeen_US
dc.contributor.authorKampon Kaeoketen_US
dc.contributor.authorMasanori Kameokaen_US
dc.contributor.authorKazuyoshi Ikutaen_US
dc.contributor.authorPathom Sawanpanyalerten_US
dc.contributor.otherThailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections (RCC-ERTen_US
dc.contributor.otherOsaka Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherThailand Ministry of Public Healthen_US
dc.date.accessioned2018-09-13T06:44:01Z-
dc.date.available2018-09-13T06:44:01Z-
dc.date.issued2009-04-01en_US
dc.identifier.citationJournal of Medical Virology. Vol.81, No.4 (2009), 657-664en_US
dc.identifier.issn10969071en_US
dc.identifier.issn01466615en_US
dc.identifier.other2-s2.0-62849092317en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=62849092317&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/27726-
dc.description.abstractHepatitis E virus (HEV) infection in pigs was investigated in two principal swine farming areas in Thailand. Anti-HEV antibodies and HEV RNA in sera were examined in 258 pigs reared on five commercial farms from age 1 to 6.5 months and sows. Overall, 167 of 258 (64.7%) pigs were positive for anti-HEV IgG, while 20 of 258 (7.75%) had detectable HEV RNA. Sequence analysis of 20 HEV isolates obtained from viremic pigs revealed thatthey were 92.3-100% identical to each other and had 82.2-88.2% nucleotide similarity to other reported genotype 3 isolates in 415 nucleotide sequences within ORF2 region. Further characterization by sequencing the complete genome of the Thai swine HEV isolate (named Thai-swHEV07) and phylogenetic analysis showed that Thai-swHEV07 segregated into a cluster consisting of swine isolates from Japan, Mongolia, and Kyrgyzstan within the HEV genotype 3. The Thai-swHEV07 had a genomic length of 7,229 nt excluding the polyadenylated region at 3' terminus of the genome. Comparison of Thai-swHEV07 and 27 reported strains of genotype 3 revealed 80.4-85.9% nucleotide identity, with the highest identity of 85.9% to the novel swHEV strain from Mongolia. These findings suggest that genotype 3 HEV isolates are markedly heterogeneous. © 2009 Wiley-Liss, Inc.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=62849092317&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleFull-length sequence of genotype 3 hepatitis e virus derived from a pig in Thailanden_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1002/jmv.21428en_US
Appears in Collections:Scopus 2006-2010

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