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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/27735
Title: Cost-effectiveness of artesunate for the treatment of severe malaria
Authors: Y. Lubell
S. Yeung
A. M. Dondorp
N. P. Day
F. Nosten
E. Tjitra
Md Abul Faiz
E. Bin Yunus
N. M. Anstey
S. K. Mishra
S. Mohanty
N. J. White
A. J. Mills
London School of Hygiene & Tropical Medicine
Mahidol University
Shoklo Malaria Research Unit
Badan Penelitian Dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia
Dhaka Medical College
Chittagong Medical College
Ispat General Hospital
London Schol of Hygiene and Tropical Medicine
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Mar-2009
Citation: Tropical Medicine and International Health. Vol.14, No.3 (2009), 332-337
Abstract: Objective: To explore the cost-effectiveness of artesunate against quinine based principally on the findings of a large multi-centre trial carried out in Southeast Asia. Methods: Trial data were used to compare mortality of patients with severe malaria, treated with either artesunate or quinine. This was combined with retrospectively collected cost data to estimate the incremental cost per death averted with the use of artesunate instead of quinine. Results: The incremental cost per death averted using artesunate was approximately 140 USD. Artesunate maintained this high level of cost-effectiveness also when allowing for the uncertainty surrounding the cost and effectiveness assessments. Conclusion: This analysis confirms the vast superiority of artesunate for treatment of severe malaria from an economic as well as a clinical perspective. © 2009 Blackwell Publishing Ltd.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=60349111924&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/27735
ISSN: 13653156
13602276
Appears in Collections:Scopus 2006-2010

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