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Title: A 2008 questionnaire-based survey of gastroesophageal reflux disease and related diseases by physicians in east asian countries
Authors: Yasuhiro Fujiwara
Shin Ichi Takahashi
Tetsuo Arakawa
Jose D. Sollano
Qi Zhu
Udom Kachintorn
Abdul Aziz Rani
Ki Baik Hahm
Takashi Joh
Yoshikazu Kinoshita
Takayuki Matsumoto
Yuji Naito
Koji Takeuchi
Kenji Furuta
Akira Terano
University of Santo Tomas, Manila
Shanghai Jiao Tong University School of Medicine
Mahidol University
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
Gachon University
Osaka City University
Kyorin University School of Medicine
Nagoya City University Graduate School of Medical Sciences
Shimane University School of Medicine
Hyogo College of Medicine
Kyoto Prefectural University of Medicine
Kyoto Pharmaceutical University
Dokkyo Medical University
Keywords: Medicine
Issue Date: 1-Oct-2009
Citation: Digestion. Vol.80, No.2 (2009), 119-128
Abstract: Background/Aims: Gastroesophageal reflux disease (GERD) is a common gastrointestinal disease. This study was designed to examine current epidemiology, diagnosis, management, and treatment of patients diagnosed with GERD by surveying physicians in several East Asian countries. Methods: A questionnaire-based survey was completed in six countries including China, Indonesia, Japan, Korea, the Philippines, and Thailand between July 2008 and December 2008. Results: In total, 876 physicians participated in the study. Most physicians in all countries, except Japan, frequently used international guidelines for the care of GERD patients, whereas approximately half of Japanese physicians did not use such guidelines. GERD was common among many patients, but Barrett's esophagus, particularly the long-segmental type, was rare. The incidence of esophageal cancer, particularly adenocarcinoma, was high in China, but low in other countries. Most physicians diagnosed GERD based on symptoms, followed by endoscopy in Japan and Korea, or in other countries, by the proton-pump inhibitor (PPI) test. Heartburn was recognized as the chief complaint in all countries except Korea. Most physicians in all countries used PPI as the first-line of treatment for GERD. Increasing the PPI dose was the treatment of choice for PPI-refractory erosive esophagitis in Korea, the Philippines, and Thailand. In contrast, in other countries, physicians used a combination of PPI and other drugs to treat PPI-refractory erosive esophagitis. Prescription of antidepressant drugs increased for PPI-refractory nonerosive reflux disease compared with PPI-refractory erosive esophagitis. Conclusion: The findings in the present survey are useful to understand the current epidemiology, diagnosis, and treatment of GERD in East Asian countries. © 2009 S. Karger AG, Basel.
ISSN: 00122823
Appears in Collections:Scopus 2006-2010

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