Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/28067
Title: What is the optimal therapy for patients with H5N1 influenza?
Authors: Nicholas J. White
Robert G. Webster
Elena A. Govorkova
Timothy M. Uyeki
Mahidol University
St. Jude Children's Research Hospital
National Center for Immunization and Respiratory Diseases
Keywords: Medicine
Issue Date: 1-Jun-2009
Citation: PLoS Medicine. Vol.6, No.6 (2009)
Abstract: Background: to the debate: In a 2007 article in PLoS Medicine [10], Holger J. Schünemann and colleagues described a new process used by the World Health Organization for rapidly developing clinical management guidelines in emergency situations. These situations include outbreaks of emerging infectious diseases. The authors discussed how they developed such a "rapid advice" guideline for the pharmacological management of avian influenza A (H5N1) virus infection. The guideline recommends giving the antiviral drug oseltamivir at a dose of 75 mg twice daily for five days. In this Debate, Nicholas White argues that such dosing is inadequate, Robert Webster and Elena Govorkova say that combination antiviral therapy should be used, and Tim Uyeki reminds us that clinical care of patients with H5N1 entails much more than antiviral treatment. These issues may also apply to therapy of patients hospitalized with severe disease due to novel swine-origin influenza A (H1N1) virus infection. © 2009 White et al.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67650217954&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/28067
ISSN: 15491676
15491277
Appears in Collections:Scopus 2006-2010

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.