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Title: A questionnaire-based survey on the prescription of non-steroidal anti-inflammatory drugs by physicians in east asian countries in 2007
Authors: Tetsuo Arakawa
Yasuhiro Fujiwara
Jose D. Sollano
Qi Zhu
Udom Kachintorn
Abdul Aziz Rani
Ki Baik Hahm
Shin Ichi Takahashi
Takashi Joh
Yoshikazu Kinoshita
Takayuki Matsumoto
Yuji Naito
Koji Takeuchi
Hirokazu Yamagami
Nenny Agustanti
Huifang Xiong
Xi Chen
Eun Jung Jang
Kenji Furuta
Akira Terano
Osaka City University
University of Santo Tomas, Manila
Shanghai Second Medical University
Mahidol University
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
Daejin Medical Center
Kyorin University
Nagoya City University
Shimane University School of Medicine
Hyogo College of Medicine
Kyoto Prefectural University of Medicine
Kyoto Pharmaceutical University
Dokkyo Medical University
Keywords: Medicine
Issue Date: 1-Apr-2009
Citation: Digestion. Vol.79, No.3 (2009), 177-185
Abstract: Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin are widely used clinically but increase the risk of gastrointestinal (GI) complications. Aim: To examine the current prescription of NSAIDs and comedication to prevent GI complications from NSAIDs within East Asia by means of a questionnaire survey. Methods: Representative members of the Committee of the International Gastrointestinal Consensus Symposium provided a questionnaire to physicians in 6 East Asian countries. Results: A total of 1,568 physicians participated in this survey. Most physicians prescribed nonselective NSAIDs, cyclooxygenase-2 inhibitors (COXIBs) or aspirin for more than 5 patients per week in all countries, with the exception of the prescription of COXIBs in Japan. Of the nonselective NSAIDs, the drug most frequently prescribed as a first choice was loxoprofen (34%), which was mainly prescribed in Japan, followed by diclofenac (30%). The frequency of prescription of comedication with nonselective NSAIDs was higher compared with that for selective COXIBs or aspirin. Physicians in the northern region (China, Japan and Korea) preferred mucoprotective drugs for comedication with NSAIDs or aspirin, while those in southern region (Indonesia, Philippines and Thailand) frequently used proton-pump inhibitors. Conclusion: Among East Asian countries, there are both similarities and differences in the prescription of NSAIDs and of comedication to prevent GI complications. Copyright © 2009 S. Karger AG, Basel.
ISSN: 00122823
Appears in Collections:Scopus 2006-2010

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