Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/28259
Title: Three novel single nucleotide polymorphisms of UGT1A9 in a Thai population
Authors: Porntipa Korprasertthaworn
Wandee Udomuksorn
Krongtong Yoovathaworn
Mahidol University
Prince of Songkla University
Keywords: Medicine;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Jan-2009
Citation: Drug Metabolism and Pharmacokinetics. Vol.24, No.5 (2009), 482-485
Abstract: The human UDP-glucuronosyltransferase, UGT1A9, catalyzes glucuronidation of various endobiotics and xenobiotics. In this study, we sequenced the promoter and exon 1 regions of the UGT1A9 gene in 93 Thai individuals and identified 7 genetic polymorphisms. The allele frequencies of all 3 novel single nucleotide polymorphisms (SNPs): 454A>G and 455A>C (N152A) and 760C>T (R254X) were 0.005. The other 4 known polymorphisms, -688A>C, 440T>C, 331C>T -118A(T)10AT (UGT1A9*1b), were identified and found to have frequencies of 0.124, 0.978, 0.968 and 0.532, respectively.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=71449126247&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/28259
ISSN: 18800920
13474367
Appears in Collections:Scopus 2006-2010

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.