Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/28380
Title: Mapping human genetic diversity in Asia
Authors: Mahmood Ameen Abdulla
Ikhlak Ahmed
Anunchai Assawamakin
Jong Bhak
Samir K. Brahmachari
Gayvelline C. Calacal
Amit Chaurasia
Chien Hsiun Chen
Jieming Chen
Yuan Tsong Chen
Jiayou Chu
Eva Maria C. Cutiongco-de La Paz
Maria Corazon A. De Ungria
Frederick C. Delfin
Juli Edo
Suthat Fuchareon
Ho Ghang
Takashi Gojobori
Junsong Han
Sheng Feng Ho
Boon Peng Hoh
Wei Huang
Hidetoshi Inoko
Pankaj Jha
Timothy A. Jinam
Li Jin
Jongsun Jung
Daoroong Kangwanpong
Jatupol Kampuansai
Giulia C. Kennedy
Preeti Khurana
Hyung Lae Kim
Kwangjoong Kim
Sangsoo Kim
Woo Yeon Kim
Kuchan Kimm
Ryosuke Kimura
Tomohiro Koike
Supasak Kulawonganunchai
Vikrant Kumar
Poh San Lai
Jong Young Lee
Sunghoon Lee
Edison T. Liu
Partha P. Majumder
Kiran Kumar Mandapati
Sangkot Marzuki
Wayne Mitchell
Mitali Mukerji
Kenji Naritomi
Chumpol Ngamphiw
Norio Niikawa
Nao Nishida
Bermseok Oh
Sangho Oh
Jun Ohashi
Akira Oka
Rick Ong
Carmencita D. Padilla
Prasit Palittapongarnpim
Henry B. Perdigon
Maude Elvira Phipps
Eileen Png
Yoshiyuki Sakaki
Jazelyn M. Salvador
Yuliana Sandraling
Vinod Scaria
Mark Seielstad
Mohd Ros Sidek
Amit Sinha
Metawee Srikummool
Herawati Sudoyo
Sumio Sugano
Helena Suryadi
Yoshiyuki Suzuki
Kristina A. Tabbada
Adrian Tan
Katsushi Tokunaga
Sissades Tongsima
Lilian P. Villamor
Eric Wang
Ying Wang
Haifeng Wang
Jer Yuarn Wu
Huasheng Xiao
Shuhua Xu
Jin Ok Yang
Yin Yao Shugart
Hyang Sook Yoo
Wentao Yuan
Guoping Zhao
Bin Alwi Zilfalil
University of Malaya
Institute of Genomics and Integrative Biology India
Mahidol University
Thailand National Center for Genetic Engineering and Biotechnology
Korea Research Institute of Bioscience and Biotechnology
University of the Philippines Diliman
Institute of Biomedical Sciences Academia Sinica Taiwan
Genome Institute of Singapore
Chinese Academy of Medical Sciences
University of the Philippines Manila
Research Organization of Information and Systems
National Institute of Advanced Industrial Science and Technology
National Engineering Center for Biochip at Shanghai
School of Medical Sciences - Universiti Sains Malaysia
Chinese National Human Genome Center at Shanghai
Tokai University School of Medicine
Fudan University
Korea National Institute of Health
Chiang Mai University
Thermo Fisher Scientific
Veracyte, Inc.
Soongsil University
Eulji University
University of Tokyo
Yong Loo Lin School of Medicine
DSO National Laboratories
Indian Statistical Institute, Kolkata
Eijkman Institute for Molecular Biology
Experimental Therapeutics Centre
Nanyang Technological University School of Computer Engineering
University of the Ryukyus Faculty of Medicine
Thailand National Science and Technology Development Agency
Monash University Malaysia
RIKEN Genomic Sciences Center
Shanghai Institute for Biological Sciences Chinese Academy of Sciences
National Institute of Mental Health
Health Sciences University of Hokkaido
Keywords: Multidisciplinary
Issue Date: 11-Dec-2009
Citation: Science. Vol.326, No.5959 (2009), 1541-1545
Abstract: Asia harbors substantial cultural and linguistic diversity, but the geographic structure of genetic variation across the continent remains enigmatic. Here we report a large-scale survey of autosomal variation from a broad geographic sample of Asian human populations. Our results show that genetic ancestry is strongly correlated with linguistic affiliations as well as geography. Most populations show relatedness within ethnic/linguistic groups, despite prevalent gene flow among populations. More than 90% of East Asian (EA) haplotypes could be found in either Southeast Asian (SEA) or Central-South Asian (CSA) populations and show clinal structure with haplotype diversity decreasing from south to north. Furthermore, 50% of EA haplotypes were found in SEA only and 5% were found in CSA only, indicating that SEA was a major geographic source of EA populations.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=72149083621&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/28380
ISSN: 10959203
00368075
Appears in Collections:Scopus 2006-2010

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