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Title: Bioactivity evaluation of eclipta prostrata linn: A potential vasorelaxant
Authors: Supaluk Prachayasittikul
Orapin Wongsawatkul
Thummaruk Suksrichavalit
Somsak Ruchirawat
Virapong Prachayasittikul
Srinakharinwirot University
Mahidol University
Chulabhorn Graduate Institute
Keywords: Agricultural and Biological Sciences;Computer Science;Earth and Planetary Sciences;Engineering;Materials Science;Mathematics
Issue Date: 1-Jan-2010
Citation: European Journal of Scientific Research. Vol.44, No.2 (2010), 167-176
Abstract: Eclipta prostrata Linn (Compositae), a traditional medicine has been used for treatment of diverse symptoms e.g. hyperlipidemia, atherosclerosis and skin diseases. This study, hexane extract of E. prostrata Linn was evaluated for bioactivities. The extract showed its new action as a potential vasorelaxant. Moreover, antioxidative (SOD and DPPH assays) and cytotoxic activities of the extract were also observed. Isolation of the extract provided a stigmasterol including eight fractions of triterpenoids along with long chain hydrocarbons. All the fractions exhibited antimicrobial activity with minimum inhibitory concentration (MIC) range of 64-256 μg/mL. The results imply therapeutic value of the plant species as an alternative medicinal source of potential vasorelaxants. © EuroJournals Publishing, Inc. 2010.
ISSN: 1450202X
Appears in Collections:Scopus 2006-2010

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