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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/28731
Title: Serotype coverage of pneumococcal conjugate vaccine and drug susceptibility of Streptococcus pneumoniae isolated from invasive or non-invasive diseases in central Thailand, 2006-2009
Authors: Somporn Srifeungfung
Chanwit Tribuddharat
Sopita Comerungsee
Tanittha Chatsuwan
Vipa Treerauthanaweeraphong
Pimpha Rungnobhakhun
Pongpun Nunthapisud
Kulkanya Chokephaibulkit
Mahidol University
Chulalongkorn University
Queen Sirikit National Institute of Child Health
Bhumipol Aduljadej Hospital
Keywords: Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine
Issue Date: 26-Apr-2010
Citation: Vaccine. Vol.28, No.19 (2010), 3440-3444
Abstract: The serotype of 172 S. pneumoniae isolates obtained from normally sterile sites from January 2006 to February 2009 in Thai patients was evaluated. The most common serotypes were 6B, 23F, 14, 19F, and 19A in patients <5 year-old, and 6B, 19A, 23F, 4, 9V in patients >65-year old. Seven-valent pneumococcal conjugated vaccine (PCV-7) covered 70.3%, 43.6%, and 43.5% of patients <5, 5-64 and ≥65 years of age, respectively, while PCV-13 covered 81.2%, 59.7%, and 60.9%, respectively. PCV-9, PCV-10, PCV-11 had very similar coverage as PCV-7. The antibiotic susceptibility rates of the isolates from sterile sites were 88.7-95.7% for penicillin, 90.6-98.4% for cefotaxime, 92.2-100% for ofloxacin and 100% for ciprofloxacin. PCV-7 covered 83% and 100%, respectively, of penicillin and cefotaxime non-susceptible isolates in patients <5-year old. © 2010 Elsevier Ltd. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950515964&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/28731
ISSN: 0264410X
Appears in Collections:Scopus 2006-2010

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