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dc.contributor.authorRatchanaporn Chokchaisirien_US
dc.contributor.authorNattawara Chaneiamen_US
dc.contributor.authorSaovaros Svastien_US
dc.contributor.authorSuthat Fucharoenen_US
dc.contributor.authorJim Vadolasen_US
dc.contributor.authorApichart Suksamrarnen_US
dc.contributor.otherRamkhamhaeng Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherRoyal Children's Hospital, Melbourneen_US
dc.date.accessioned2018-09-24T08:45:59Z-
dc.date.available2018-09-24T08:45:59Z-
dc.date.issued2010-04-23en_US
dc.identifier.citationJournal of Natural Products. Vol.73, No.4 (2010), 724-728en_US
dc.identifier.issn15206025en_US
dc.identifier.issn01633864en_US
dc.identifier.other2-s2.0-77951613688en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77951613688&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/28733-
dc.description.abstractThree new labdane diterpenes, curcucomosins A-C (1-3), four known labdane diterpenes, 4-7, and a known diarylheptanoid, 8, were isolated from the aerial parts of Curcuma comosa. The structures of the new diterpenes were elucidated by spectroscopic data analysis. The fetal hemoglobin (Hb F) induction potency of the isolated compounds was examined using a K562 reporter cell line harboring the enhanced green fluorescence protein (EGFP) gene under the control of a Gγ-globin promoter. Compound 6, isocoronarin D, exhibited the highest Hb F induction effect of 1.6-fold at 20 μM. © 2010 The American Chemical Society and American Society of Pharmacognosy.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77951613688&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleLabdane diterpenes from the aerial parts of curcuma comosa enhance fetal hemoglobin production in an erythroid cell lineen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1021/np900568ken_US
Appears in Collections:Scopus 2006-2010

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