Please use this identifier to cite or link to this item:
|Title:||Accuracy of accessbio immunoglobulin M and total antibody rapid immunochromatographic assays for the diagnosis of acute scrub typhus infection|
|Authors:||Stuart D. Blacksell|
Nicholas P.J. Day
Paul N. Newton
Wei Mei Ching
University of Oxford
Naval Medical Research Center
|Keywords:||Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine|
|Citation:||Clinical and Vaccine Immunology. Vol.17, No.2 (2010), 263-266|
|Abstract:||Using archived samples, we assessed the diagnostic capacity of a rapid immunochromatographic test (ICT) for the detection of Orientia tsutsugamushi IgM and total antibodies to aid with the diagnosis of acute scrub typhus infection in febrile patients in Laos. The sensitivity and the specificity of the ICT for the detection of IgM were 96.8% (121/125 samples; 95% confidence interval [CI], 92.1 to 99.1%) and 93.3% (98/105 samples; 95% CI, 86.7 to 97.3%), respectively. For the detection of total antibodies, the sensitivity was 97.6% (122/125 samples; 95% CI, 93.1 to 99.5%), but the specificity was much lower, at 71.4% (75/105 samples; 95% CI, 61.8 to 79.8%). Copyright © 2010, American Society for Microbiology. All Rights Reserved.|
|Appears in Collections:||Scopus 2006-2010|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.