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Title: Curvularides A-E: Antifungal hybrid peptide-polyketides from the endophytic fungus Curvularia geniculata
Authors: Porntep Chomcheon
Suthep Wiyakrutta
Thammarat Aree
Nongluksna Sriubolmas
Nattaya Ngamrojanavanich
Chulabhorn Mahidol
Somsak Ruchirawat
Prasat Kittakoop
Chulabhorn Research Institute
Rajabhat University
Mahidol University
Chulalongkorn University
Keywords: Chemistry
Issue Date: 24-Sep-2010
Citation: Chemistry - A European Journal. Vol.16, No.36 (2010), 11178-11185
Abstract: Five new hybrid peptide-polyketides, curvularides A-E (1-5), were isolated from the endophytic fungus Curvularia geniculata, which was obtained from the limbs of Catunaregam tomentosa. Structure elucidation for curvularides A-E (1-5) was accomplished by analysis of spectroscopic data, as well as by single-crystal X-ray crystallography. Curvularide B (2) exhibited antifungal activity against Candida albicans, and it also showed synergistic activity with a fluconazole drug. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA. Weinheim.
ISSN: 15213765
Appears in Collections:Scopus 2006-2010

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