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dc.contributor.authorYouthanavanh Vonghachacken_US
dc.contributor.authorParon Dekumyoyen_US
dc.contributor.authorTippayarat Yoonuanen_US
dc.contributor.authorSurapol Sa-nguankiaten_US
dc.contributor.authorSupaporn Nuamtanongen_US
dc.contributor.authorUrusa Thaenkhamen_US
dc.contributor.authorBounlay Phommasacken_US
dc.contributor.authorJun Kobayashien_US
dc.contributor.authorJitra Waikagulen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUniversity of Health Sciencesen_US
dc.contributor.otherMinistry of Healthen_US
dc.contributor.otherNational Center for Global Health and Medicineen_US
dc.identifier.citationParasitology International. Vol.59, No.4 (2010), 599-605en_US
dc.description.abstractWhile human gnathostomiasis cases have been reported sporadically in Lao PDR since 1975, little is known about the disease in this country. We aimed to investigate sero-prevalence of gnathostomiasis and Gnathostoma species in Lao PDR. One village each in the north, central and south regions of Lao PDR was selected as the study sites. Overall, 125 (29.8%) of 420 sera from the randomly selected participants were sero-positive by immunoblot technique, with anti-Gnathostoma IgG antibody against the 24. kDa fraction. The sero-prevalence was high in the central (47.1%) and south (38.6%), but low (3.6%) in the north. Risk factor analyses revealed that the consumption of raw/undercooked fish was significantly associated with Gnathostoma sero-positivity (95% CI 1.05-17.05, P=0.042). The sero-positivity significantly increased with the age of the participants. Several fish, swamp eels, and frogs collected from central and southern Lao were infected with G. spinigerum advanced 3rd-stage larvae. Channa limbata (red-tailed snakehead fish) was identified as a natural second intermediate host of G. spinigerum. Eggs of G. spinigerum were found in dog feces collected in the south. Gnathostomiasis is endemic in central and southern Laos, so that preventive measures should be introduced for people living in these regions. © 2010 Elsevier Ireland Ltd.en_US
dc.rightsMahidol Universityen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleSero-epidemiological survey of gnathostomiasis in Lao PDRen_US
Appears in Collections:Scopus 2006-2010

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