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Title: Haplorchis taichui as a possible etiologic agent of irritable bowel syndrome-like symptoms
Authors: Dorn Watthanakulpanich
Jitra Waikagul
Wanna Maipanich
Supaporn Nuamtanong
Surapol Sanguankiat
Somchit Pubampen
Rangson Praevanit
Srisuchat Mongkhonmu
Yukifumi Nawa
Mahidol University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Sep-2010
Citation: Korean Journal of Parasitology. Vol.48, No.3 (2010), 225-229
Abstract: The aim of this study is to clarify the clinical features of Haplorchis taichui infection in humans in Nan Province, Thailand, and to correlate the clinical features with irritable bowel syndrome (IBS)-like symptoms. In this study area, only H. taichui, but neither other minute intestinal flukes nor small liver flukes were endemic. The degree of infection was determined by fecal egg counts and also by collecting adult worms after deworming. The signs and symptoms of individual patients together with their hematological and biochemical laboratory data were gathered to evaluate the relationship between the clinical features and the severity of infection. Special emphasis was made to elucidate the possible similarities of the clinical features of H. taichui infection and IBS-like symptoms. The results showed useful clinical information and the significant (> 50%) proportion of haplorchiasis patients complained of abdominal pain, lassitude, and flatulence, which were the important diagnostic symptoms of IBS. This study has reported a possible link between H. taichui and IBS, and H. taichui might probably play a role in the etiology of these IBS-like symptoms.
ISSN: 17380006
Appears in Collections:Scopus 2006-2010

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