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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/29264
Title: Comparison between siriraj mite allergen vaccine and standardized commercial mite vaccine by skin prick testing in normal thai adults
Authors: Nualanong Visitsunthorn
Punchama Pacharn
Orathai Jirapongsananuruk
Sirirat Weeravejsukit
Chaweewan Sripramong
Nitat Sookrung
Chaweewan Bunnag
Division of Allergy and Immunology
Office for Research and Development
Mahidol University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Mar-2010
Citation: Asian Pacific Journal of Allergy and Immunology. Vol.28, No.1 (2010), 41-45
Abstract: House dust mite is a major cause of allergic asthma and rhinitis in Thai population. Skin prick test (SPT) is a useful tool for the diagnosis of the IgE-mediated reactions. The imported commercial mite vaccine for SPT is available but it is relatively expensive. Aim of this studyis to compare Siriraj Mite Allergen Vaccine (SMAV) with standardized commercial mite allergen vaccine by skin prick testing in normal Thai adults. A double blind, self-controlled study between the SMAV and standardized commercial mite allergen vaccine was performed by SPT in 17 normal Thai adult males and non-pregnant or non-lactating females aged 18-60 years. The study showed that 35.29 % of non atopic adults had positive SPT reaction to Dp and Df of both SMAV andstandardized commercial mite allergen vaccine. Mean wheal and flare diameters from SPT of Dp and Df of SMAV showed strong correlation with standardized commercial mite allergen vaccine (r = 0.768 and 0.897 in Dp and Df respectively, p <0.001). The intraclass correlation was also excellent (0.893 and 0.775 in Dp and Df respectively). There was no significant difference in wheal and flare diameter between SMAV andstandardized commercial mite allergen vaccine. No systemic or large local reaction was found in any of the study cases.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954543833&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/29264
ISSN: 0125877X
Appears in Collections:Scopus 2006-2010

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