Please use this identifier to cite or link to this item:
|Title:||The dynamics of a nonlinear model of signal transduction in human under impulsive depressant drug treatment|
PERDO Commission on Higher Education
|Citation:||Dynamic Systems and Applications. Vol.19, No.3-4 (2010), 651-666|
|Abstract:||A mathematical model of the signal transduction process, involving hormone coupled receptors and an inhibiting enzyme, under impulsive depressant treatment, is proposed and analyzed. We show that there is a stable periodic solution, at the vanishing density of the ligand bound receptors on the cell membrane and plasmalemma, when the impulsive period is less than some critical value. The conditions for permanence of the system are then given. Finally, it is shown that as the impulsive period increases beyond a certain critical value, the emergence of stable positive periodic solution may be observed under appropriate conditions on the system parameters. © Dynamic Publishers, Inc.|
|Appears in Collections:||Scopus 2006-2010|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.