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|Title:||Partial "targeted" embolisation of brain arteriovenous malformations|
Franz Josef Hans
University of Toronto
Medizinische Fakultat und Universitats Klinikum Aachen
Hospital for Sick Children University of Toronto
|Citation:||European Radiology. Vol.20, No.11 (2010), 2723-2731|
|Abstract:||The treatment of pial arteriovenous brain malformations is controversial. Little is yet known about their natural history, their pathomechanisms and the efficacy and risks of respective proposed treatments. It is known that only complete occlusion of the AVM can exclude future risk of haemorrhage and that the rates of curative embolisation of AVMs with an acceptable periprocedural risk are around 20 to 50%. As outlined in the present article, however, partial, targeted embolisation also plays a role. In acutely ruptured AVMs where the source of bleeding can be identified, targeted embolisation of this compartment may be able to secure the AVM prior to definitive treatment. In unruptured symptomatic AVMs targeted treatment may be employed if a defined pathomechanism can be identified that is related to the clinical symptoms and that can be cured with an acceptable risk via an endovascular approach depending on the individual AVM angioarchitecture. This review article gives examples of pathomechanisms and angioarchitectures that are amenable to this kind of treatment strategy. © 2010 The Author(s).|
|Appears in Collections:||Scopus 2006-2010|
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