Please use this identifier to cite or link to this item:
|Title:||High prevalence of CTX-M β-lactamase-producing enterobacteriaceae in stool specimens obtained from healthy individuals in Thailand|
Osaka University Faculty of Medicine
Kobe University School of Medicine
Kansai Medical University
|Keywords:||Medicine;Pharmacology, Toxicology and Pharmaceutics|
|Citation:||Journal of Antimicrobial Chemotherapy. Vol.65, No.4 (2010), 666-668|
|Abstract:||Objectives: To determine the prevalence of CTX-M β-lactamase-producing Enterobacteriaceae in stool specimens obtained from healthy individuals in a rural area of Thailand. Methods: Bacteria in stool specimens were screened for extended-spectrum β-lactamase (ESBL) production on McConkey agar with cefotaxime and confirmed by the double-disc synergy test. Genetic detection and genotyping of CTX-M-type ESBL was performed by PCR with bacterial DNA extracted from isolates. Results: A markedly high number (82 of 141, 58.2%) of the specimens showed the presence of CTX-M β-lactamase-producing Enterobacteriaceae, as confirmed by both phenotypic and genetic examinations. The majority of the CTX-M β-lactamase-producing bacteria were Escherichia coli (85.1%). Conclusions: The study revealed the wide dissemination of CTX-M β-lactamase-producing Enterobacteriaceae in the healthy population. © The Author 2010. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.|
|Appears in Collections:||Scopus 2006-2010|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.