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dc.contributor.authorTadahiro Sasakien_US
dc.contributor.authorItaru Hiraien_US
dc.contributor.authorMarie Nikien_US
dc.contributor.authorTatsuya Nakamuraen_US
dc.contributor.authorChalit Komalamisraen_US
dc.contributor.authorWanna Maipanichen_US
dc.contributor.authorTeera Kusolsuken_US
dc.contributor.authorSurapol Sa-nguankiaten_US
dc.contributor.authorSomchit Pubampenen_US
dc.contributor.authorYoshimasa Yamamotoen_US
dc.contributor.otherOsaka University Faculty of Medicineen_US
dc.contributor.otherKobe University School of Medicineen_US
dc.contributor.otherKansai Medical Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.identifier.citationJournal of Antimicrobial Chemotherapy. Vol.65, No.4 (2010), 666-668en_US
dc.description.abstractObjectives: To determine the prevalence of CTX-M β-lactamase-producing Enterobacteriaceae in stool specimens obtained from healthy individuals in a rural area of Thailand. Methods: Bacteria in stool specimens were screened for extended-spectrum β-lactamase (ESBL) production on McConkey agar with cefotaxime and confirmed by the double-disc synergy test. Genetic detection and genotyping of CTX-M-type ESBL was performed by PCR with bacterial DNA extracted from isolates. Results: A markedly high number (82 of 141, 58.2%) of the specimens showed the presence of CTX-M β-lactamase-producing Enterobacteriaceae, as confirmed by both phenotypic and genetic examinations. The majority of the CTX-M β-lactamase-producing bacteria were Escherichia coli (85.1%). Conclusions: The study revealed the wide dissemination of CTX-M β-lactamase-producing Enterobacteriaceae in the healthy population. © The Author 2010. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.en_US
dc.rightsMahidol Universityen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleHigh prevalence of CTX-M β-lactamase-producing enterobacteriaceae in stool specimens obtained from healthy individuals in Thailanden_US
Appears in Collections:Scopus 2006-2010

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