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|Title:||Therapeutic drug monitoring of lopinavir in human immunodeficiency virus-infected children receiving adult tablets|
The HIV Netherlands Australia Thailand Research Collaboration
Thailand Ministry of Public Health
|Citation:||Pediatric Infectious Disease Journal. Vol.29, No.1 (2010), 79-82|
|Abstract:||Because of the lack of a lopinavir/ritonavir (LPV/r) pediatric formulation, 54 HIV-infected children were given generic LPV/r adult tablets. Of 54 children, 21 took cut pills to get the appropriate dose. The median (interquartile range) LPV trough serum concentration (Ctrough) was 6.7 (5.0-9.9) mg/L. All the children had Ctrough >1.0 mg/L and 96% had values >4.0 mg/L. LPV/r adult tablets can be used in children when it is necessary. © 2009 by Lippincott Williams & Wilkins.|
|Appears in Collections:||Scopus 2006-2010|
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