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Title: Immunopathology of acute rheumatic fever and rheumatic heart disease. The demonstration of Coxsackie group B viral antigen in the myocardium
Authors: B. Pongpanich
S. Boonpucknavig
C. Wasi
P. Tanphaichitr
V. Boonpucknavig
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Mahidol University
Keywords: Medicine
Issue Date: 1-Sep-1983
Citation: Clinical Rheumatology. Vol.2, No.3 (1983), 217-222
Abstract: Immunopathologic studies were performed on heart tissue of patients with acute rheumatic fever with carditis and chronic rheumatic heart disease. Coxsackie group B viral antigen was demonstrated in 3 heart specimens of patients clinically compatible with active rheumatic fever. In two of these the pathologic findings were compatible with acute rheumatic carditis. Immunoglobulin was detected in 2 and complement in one of these heart specimens. All of the chronic rheumatic heart specimens and the controls were negative. These findings suggested that Coxsackie group B virus may be etiologically related to the pathogenesis of acute rheumatic fever. © 1983 Springer-Verlag.
ISSN: 14349949
Appears in Collections:Scopus 1969-1990

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