Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/3062
Title: Antioxidant effects of aqueous extracts from dried calyx of hibiscus sabdariffa LINN. (Roselle) in vitro using rat low-density lipoprotein (LDL)
Authors: Vilasinee Hirunpanich
Anocha Utaipat
Noppawan Phumala Morales
Nantavan Bunyapraphatsara
Sato, Hitoshi
Angkana Herunsalee
Chuthamanee Suthisisang
วิลาสินี หิรัญพานิช
อโนชา อุทัยพัฒน์
นันทวัน บุณยะประภัศร
จุฑามณี สุทธิสีสังข์
Mahidol University. Faculty of Pharmacy. Department of Pharmacology.
Mahidol University. Faculty of Pharmacy. Department of Pharmacognosy
Mahidol University. Facutly of Science. Department of Pharmacology
Keywords: Hibiscus sabdariffa;Roselle;Low-density Lipoprotein(LDL) Oxidation;Antioxidants
Issue Date: 5-Aug-2010
Citation: Biological and Pharmaceutical Bulletin. Vol.28, No.3 (2005), 481-4
Abstract: The present study quantitatively investigated the antioxidant effects of the aqueous extracts from dried calyx of Hibiscus sabdariffa LINN. (roselle) in vitro using rat low-density lipoprotein (LDL). Formations of the conjugated dienes and thiobarbituric acid reactive substances (TBARs) were monitored as markers of the early and later stages of the oxidation of LDL, respectively. Thus, we demonstrated that the dried calyx extracts of roselle exhibits strong antioxidant activity in Cu2+ -mediated oxidation of LDL (p<0.05) in vitro. The inhibitory effect of the extracts on LDL oxidation was dose-dependent at concentrations ranging from 0.1 to 5 mg/ml. Moreover, 5 mg/ml of roselle inhibited TBARs-formation with greater potency than 100 mrgM of vitamin E. In conclusion, this study provides a quantitative insight into the potent antioxidant effect of roselle in vitro.
URI: http://repository.li.mahidol.ac.th/dspace/handle/123456789/3062
metadata.dc.identifier.url: https://www.jstage.jst.go.jp/article/bpb/28/3/28_3_481/_pdf
ISSN: 0918-6158
Appears in Collections:PY-Article

Files in This Item:
File Description SizeFormat 
py-ar-anocha-2005-1.pdf365.01 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.