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dc.contributor.authorVincenzo Eneaen_US
dc.contributor.authorJoan Ellisen_US
dc.contributor.authorFidel Zavalaen_US
dc.contributor.authorDavid E. Arnoten_US
dc.contributor.authorAchara Asavanichen_US
dc.contributor.authorAoi Masudaen_US
dc.contributor.authorIsabella Quakyien_US
dc.contributor.authorRuth S. Nussenzweigen_US
dc.contributor.otherNYU Langone Medical Centeren_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherNew York Universityen_US
dc.contributor.otherUniversity of Ghanaen_US
dc.date.accessioned2018-10-12T07:45:25Z-
dc.date.available2018-10-12T07:45:25Z-
dc.date.issued1984-01-01en_US
dc.identifier.citationScience. Vol.225, No.4662 (1984), 628-630en_US
dc.identifier.issn00368075en_US
dc.identifier.other2-s2.0-0021160478en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021160478&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/30722-
dc.description.abstractA clone of complementary DNA encoding the circumsporozoite (CS) protein of the human malaria parasite Plasmodium falciparum has been isolated by screening an Escherichia coli complementary DNA library with a monoclonal antibody to the CS protein. The DNA sequence of the complementary DNA insert encodes a four-amino acid sequence: proline-asparagine-alanine-asparagine, tandemly repeated 23 times. The CS β-lactamase fusion protein specifically binds monoclonal antibodies to the CS protein and inhibits the binding of these antibodies to native Plasmodium falciparum CS protein. These findings provide a basis for the development of a vaccine against Plasmodium falciparum malaria.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021160478&origin=inwarden_US
dc.subjectMultidisciplinaryen_US
dc.titleDNA cloning of plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitopeen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1126/science.6204384en_US
Appears in Collections:Scopus 1969-1990

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