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Title: A specific s-antigen of plasmodium falciparum is expressed in a proportion of primary isolates in brazil, thailand and papua new guinea
Authors: Louis Schofield
Savanat Tharavanij
Allan Saul
Virgilio Do Rosario
Chev Kidson
QIMR Berghofer Medical Research Institute
Mahidol University
Instituto Evandro Chagas
The University of North Carolina at Chapel Hill
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jan-1985
Citation: Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.79, No.4 (1985), 493-494
Abstract: The expression by Plasmodium falciparum of a specific S-antigen has been examined in primary isolates in different regions of the world using a monoclonal antibody that recognizes an epitope within a known repeated amino acid sequence. The epitope was expressed by a small proportion of primary isolates in each of Brazil, Thailand and Papua New Guinea, demonstrating that this S-antigen gene is widespread. The data are consistent with the possibility that the occurrence of P. falciparum strains expressing a particular S-antigen is periodic, related to the duration of immunity against that antigen in a given human population. © Oxford University Press.
ISSN: 18783503
Appears in Collections:Scopus 1969-1990

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