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Title: Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of triterpenoids isolated from leaves and twigs of Gardenia carinata
Authors: Naowarat Kongkum
Patoomratana Tuchinda
Manat Pohmakotr
Vichai Reutrakul
Pawinee Piyachaturawat
Surawat Jariyawat
Kanoknetr Suksen
Radeekorn Akkarawongsapat
Jitra Kasisit
Chanita Napaswad
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Medicine;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 26-Apr-2013
Citation: Journal of Natural Products. Vol.76, No.4 (2013), 530-537
Abstract: Eight new cycloartane triterpenoids (1-8), named carinatins A-H, and the known compounds secaubryolide (9) and dikamaliartane D (10) were isolated from the leaves and twigs of Gardenia carinata. Their structures were determined on the basis of spectroscopic methods. Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of compounds 1-7, 9, and 10 were investigated. © 2013 The American Chemical Society and American Society of Pharmacognosy.
ISSN: 15206025
Appears in Collections:Scopus 2011-2015

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