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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/31828
Title: Sparganosis presenting as cauda equina syndrome with molecular identification of the parasite in tissue sections
Authors: Adhiratha Boonyasiri
Pornsuk Cheunsuchon
Prajak Srirabheebhat
Hiroshi Yamasaki
Wanchai Maleewong
Pewpan M. Intapan
Mahidol University
National Institute of Infectious Diseases
Khon Kaen University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Dec-2013
Citation: Korean Journal of Parasitology. Vol.51, No.6 (2013), 739-742
Abstract: A 52-year-old woman presented with lower back pain, progressive symmetrical paraparesis with sensory impairment, and sphincter disturbance. Magnetic resonance imaging (MRI) of the whole spine revealed multiple intradural extramedullary serpiginous-mass lesions in the subarachnoid space continuously from the prepontine to the anterior part of the medulla oblongata levels, C7, T2-T8, and T12 vertebral levels distally until the end of the theca sac and filling-in the right S1 neural foramen. Sparganosis was diagnosed by demonstration of the sparganum in histopathological sections of surgically resected tissues and also by the presence of serum IgG antibodies by ELISA. DNA was extracted from unstained tissue sections, and a partial fragment of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was amplified using a primer set specific for Spirometra spp. cox1. After sequencing of the PCR-amplicon and alignment of the nucleotide sequence data, the causative agent was identified as the larva of Spirometra erinaceieuropaei. © 2013, Korean Society for Parasitology and Tropical Medicine.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84893214956&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/31828
ISSN: 17380006
00234001
Appears in Collections:Scopus 2011-2015

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