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Title: A mechanism of raft formation on both plasma membrane layers
Authors: Kan Sornbundit
Charin Modchang
Wannapong Triampo
Darapond Triampo
Narin Nuttavut
Mahidol University
South Carolina Commission on Higher Education
Keywords: Materials Science;Physics and Astronomy
Issue Date: 1-Oct-2013
Citation: EPJ Applied Physics. Vol.64, No.1 (2013)
Abstract: A double-layered membrane model is proposed to explain raft formation and induction on extracellular (outer) and cytoplasmic (inner) leaflets of plasma membranes in a situation where only the outer layer has a tendency to phase-separate. In the model, lipid exchange with the surrounding medium is allowed on both layers, but lipid exchange between layers is not allowed. Simulations display domain stabilization on both layers. The effect of the lipid recycling frequencies on stationary domain sizes is also investigated. It is found that stationary domain sizes decrease when lipid recycling frequencies are stronger. Linear stability analysis is used to verify the results. © 2013 EDP Sciences.
ISSN: 12860050
Appears in Collections:Scopus 2011-2015

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