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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/32146
Title: Immediate breast reconstruction with expander in pregnant breast cancer patients
Authors: Visnu Lohsiriwat
Fedro Alessandro Peccatori
Stefano Martella
Hatem A. Azim
Maria Anna Sarno
Viviana Galimberti
Francesca De Lorenzi
Mattia Intra
Claudia Sangalli
Nicole Rotmensz
Giancarlo Pruneri
Giuseppe Renne
Mario Casales Schorr
Luiz Felipe Nevola Teixeira
Mario Rietjens
Massimo Giroda
Oreste Gentilini
Istituto Europeo di Oncologia
Mahidol University
Universita degli Studi di Milano, Facolta di Medicina e Chirurgia
IRCCS Foundation Rome
Keywords: Medicine
Issue Date: 1-Oct-2013
Citation: Breast. Vol.22, No.5 (2013), 657-660
Abstract: Background: Breast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation. Method: We retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012. Patient demographics, gestational age at surgery, tumor stage, adjuvant treatment, details of the surgical procedures, surgical outcomes and fetal outcomes were analyzed. Results: A total of 78 patients with breast cancer diagnosed during pregnancy were subjected to a surgical procedure during the course of gestation. Twenty-two patients had mastectomy; of whom 13 were subjected to immediate breast reconstruction. Twelve out of 13 patients had a two-stage procedure with tissue expander insertion. Median gestational age at surgery was 16 weeks. No major surgical complications were encountered. Only one patient elected to have an abortion, otherwise, no spontaneous abortions or pregnancy complications were reported. Median gestational age at delivery was 35 weeks (range: 32-40 weeks). No major congenital malformations were reported. At a median follow-up of 32months, all patients are alive with no long-term surgical complications. Conclusions: This is the first study of immediate breast reconstruction in pregnant breast cancer patients. Tissue expander insertion appears to ensure a short operative time, and does not seem to be associated with considerable morbidity to the patient or the fetus. Hence, it could be considered in the multidisciplinary management of women diagnosed with breast cancer during pregnancy. © 2013 Elsevier Ltd.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84884142710&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/32146
ISSN: 15323080
09609776
Appears in Collections:Scopus 2011-2015

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