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Title: Asian Sudden Cardiac Death in Heart Failure (ASIAN-HF) registry
Authors: Carolyn S.P. Lam
Inder Anand
Shu Zhang
Wataru Shimizu
Calambur Narasimhan
Sang Weon Park
Cheuk Man Yu
Tachapong Ngarmukos
Razali Omar
Eugene B. Reyes
Bambang Siswanto
Lieng H. Ling
A. Mark Richards
Cardiovascular Research Institute
University of Minnesota Medical School
Fuwai Hospital
Kokuritsu Junkankibyo Senta
CARE Hospital
Korea University
Prince of Wales Hospital Hong Kong
Mahidol University
Institut Jantung Negara
Manila Doctors Hospital
Universitas Indonesia
Keywords: Medicine
Issue Date: 1-Aug-2013
Citation: European Journal of Heart Failure. Vol.15, No.8 (2013), 928-936
Abstract: Aims: Our aim is to determine mortality and morbidity in Asian patients under clinical management for heart failure (HF). Specifically, we will define the incidence of, and risk factors for, sudden cardiac death, as well as the socio-cultural factors influencing therapeutic choices in these patients.MethodsThis is a prospective observational multinational Asian registry of 5000 patients with symptomatic HF (stage C) and LV systolic dysfunction (EF ≤ 40%) involving 44 centres across 11 Asian regions (China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Philippines, Singapore, Taiwan and Thailand). Data collection includes demographic variables, clinical symptoms, functional status, date of HF diagnosis and prior cardiovascular investigations, clinical risk factors, lifestyle factors, socio-economic status, and survey of cultural beliefs, health practices, and attitudes towards device therapy. Centre-level characteristics (case load, referral pattern, specialization, and infrastructure) are also obtained. Patients uniformly undergo standard 12-lead ECG and transthoracic echocardiography at baseline, and are followed over 3 years for outcomes of death or hospitalization. The mode of death and cause of hospitalization are adjudicated by a central event adjudication committee using pre-specified criteria.PerspectiveBy providing prospective data regarding the demographics, risk factors, and outcomes of Asian patients under treatment for HF, the ASIAN-HF registry is expected to advance fundamental understanding of the burden and predictors of death and hospitalization among these patients. The knowledge gained will be important for guiding resource allocation and planning preventive strategies to address the unmet and growing clinical needs of patients with cardiovascular disease in Asia. © The Author 2013.
ISSN: 18790844
Appears in Collections:Scopus 2011-2015

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