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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/32593
Title: Lateral cephalometric analysis and the risks of moderate to severe obstructive sleep-disordered breathing in Thai patients
Authors: Wish Banhiran
Pisit Wanichakorntrakul
Choakchai Metheetrairut
Pipat Chiewvit
Wandee Planuphap
Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-2013
Citation: Sleep and Breathing. Vol.17, No.4 (2013), 1249-1255
Abstract: Purposes: This cross-sectional study was aimed to compare lateral cephalometric parameters among patients with different severities of obstructive sleep-disordered breathing and to determine if there are radiographic variables that increase risk of moderate to severe obstructive sleep apnea (OSA). Methods: Ten linear and 5 angular parameters of lateral cephalometry in 188 adult subjects which included 47 controls and 141 patients with OSA classified by apnea-hypopnea index (AHI) from level-I polysomnography, were analyzed. All radiographs were done under standardized processes and measured twice on separate occasions. Results: There were statistically significant differences between controls and patients with AHI ≥ 15 in parameters such as a distance from mandibular plane to hyoid (MP-H), posterior airway space (PAS), skull base angle (NSBA), a distance from posterior nasal spine to posterior pharyngeal wall (PNS-PP), and soft palate length (PNS-P), (p < 0.01). However, no significant difference was found between controls and mild OSA. Logistic regression analysis showed that only MP-H with cutoff point of ≥ 18 millimeters, NSBA ≤ 130, and PAS ≤ 10 millimeters were independent cephalometric variables that increased risk of having AHI ≥ 15 compared to controls with adjusted odds ratio of 17.1, 8.3 and 4.2, respectively. Gender did not significantly associate with OSA severity in this analysis. Conclusions: Patients who had longer MP-H, narrower PAS and narrower NSBA than specific cutoff points significantly increased risks of moderate to severe OSA. Treatments that effectively improve these parameters, particularly at tongue base level (MP-H and PAS), may decrease the severity of disease. © 2013 Springer-Verlag Berlin Heidelberg.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84888638133&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/32593
ISSN: 15221709
15209512
Appears in Collections:Scopus 2011-2015

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