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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/32740
Title: Bioautography-guided isolation of antibacterial compounds of essential oils from Thai spices against histamine-producing bacteria
Authors: Pattamapan Lomarat
Phanida Phanthong
Karn Wongsariya
Mullika Traidej Chomnawang
Nuntavan Bunyapraphatsara
Mahidol University
Keywords: Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-May-2013
Citation: Pakistan Journal of Pharmaceutical Sciences. Vol.26, No.3 (2013), 473-477
Abstract: The outbreak of histamine fish poisoning has been being an issue in food safety and international trade. The growth of contaminated bacterial species including Morganella morganii which produce histidine decarboxylase causes histamine formation in fish during storage. Histamine, the main toxin, causes mild to severe allergic reaction. At present, there is no well-established solution for histamine fish poisoning. This study was performed to determine the antibacterial activity of essential oils from Thai spices against histamine-producing bacteria. Among the essential oils tested, clove, lemongrass and sweet basil oils were found to possess the antibacterial activity. Clove oil showed the strongest inhibitory activity against Morganella morganii, followed by lemongrass and sweet basil oils. The results indicated that clove, lemongrass and sweet basil oils could be useful for the control of histamine-producing bacteria. The attempt to identify the active components using preparative TLC and GC/MS found eugenol, citral and methyl chavicol as the active components of clove, lemongrass and sweet basil oils, respectively. The information from this study would be useful in the research and development for the control of histamine-producing bacteria in fish or seafood products to reduce the incidence of histamine fish poisoning.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84878047472&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/32740
ISSN: 1011601X
Appears in Collections:Scopus 2011-2015

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