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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/33217
Title: A stereoselective approach to bioactive secolignans: Synthesis of peperomin C and its analogues
Authors: Darunee Soorukram
Jaray Panmuang
Patoomratana Tuchinda
Chutima Kuhakarn
Vichai Reutrakul
Manat Pohmakotr
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 14-Oct-2014
Citation: Tetrahedron. Vol.70, No.41 (2014), 7577-7583
Abstract: © 2014 Elsevier Ltd. All rights reserved. A stereoselective approach to secolignans is described. The key synthetic strategy involves an asymmetric aldol reaction to control the creation of the stereogenic center at the β-carbon of the target secolignans. In the present work, peperomin C and its analogues, i.e., 2,6-didehydropeperomin C and 2-epi-peperomin C were successfully synthesized in good yields with high stereoselectivities.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907059382&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/33217
ISSN: 14645416
00404020
Appears in Collections:Scopus 2011-2015

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