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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/34087
Title: Treatment of suspected hyper-reactive malarial splenomegaly (HMS) in pregnancy with mefloquine
Authors: Juthamas Jaroensuk
Nicole Stoesser
Mara L. Leimanis
Podjanee Jittamala
Nicholas J. White
Francois H. Nosten
Rose McGready
Mahidol University
John Radcliffe Hospital
Nuffield Department of Clinical Medicine
Shoklo Malaria Research Unit
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jan-2014
Citation: American Journal of Tropical Medicine and Hygiene. Vol.90, No.4 (2014), 609-611
Abstract: Malaria infections in pregnancy are associated with adverse outcomes for both mother and child. There are few data on hyper-reactive malarial splenomegaly, an aberrant immunological response to chronic or recurrent malaria in pregnancy. This retrospective assessment reviewed the impact of mefloquine treatment on pregnant women with suspected hyper-reactive malarial splenomegaly in an area of low malaria transmission in the 1990s, showing significant reductions in spleen size and anemia and anti-malarial antibody titers without any notable negative effect on treated women or their newborns. Copyright © 2014 by The American Society of Tropical Medicine and Hygiene.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84898757143&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/34087
ISSN: 00029637
Appears in Collections:Scopus 2011-2015

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