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Title: High burden of antimicrobial drug resistance in Asia
Authors: Chi Cheng Lai
Kyungwon Lee
Yonghong Xiao
Norazah Ahmad
Balaji Veeraraghavan
Visanu Thamlikitkul
Paul Ananth Tambyah
R. H.H. Nelwan
Atef M. Shibl
Jiunn Jong Wu
Wing Hong Seto
Po Ren Hsueh
Chi Mei Medical Center
Yonsei University College of Medicine
Zhejiang University
Institute for Medical Research Kuala Lumpur
Christian Medical College, Vellore
Mahidol University
National University Hospital, Singapore
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
King Saud University
National Cheng Kung University
Hong Kong Hospital Authority
National Taiwan University Hospital
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jan-2014
Citation: Journal of Global Antimicrobial Resistance. Vol.2, No.3 (2014), 141-147
Abstract: The rapid development of antimicrobial resistance among micro-organisms is a serious public health concern. Moreover, the dissemination of antibiotic-resistant bacteria makes this issue a global problem, and Asia is no exception. For example, since New Delhi metallo-β-lactamase (NDM)-producing Enterobacteriaceae were identified in India, further spread of NDM has become a worldwide threat. However, the epidemiology of antibiotic-resistant bacteria in Asia may be different to other regions, and clinical condition may be worse than in western countries. Antibiotic-resistant bacteria, including community-acquired and hospital-acquired meticillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate S. aureus (VISA), vancomycin-resistant enterococci, macrolide- and penicillin-resistant Streptococcus pneumoniae, extend-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa and Acinetobacter spp., are becoming prevalent in many countries in Asia. Moreover, the prevalence of each antibiotic-resistant bacterium in each country is not identical. This review provides useful information regarding the critical condition of antibiotic resistance in Asia and emphasises the importance of continuous surveillance of resistance data. © 2014 International Society for Chemotherapy of Infection and Cancer.
ISSN: 22137173
Appears in Collections:Scopus 2011-2015

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