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|Title:||Microevolution of Burkholderia pseudomallei during an acute infection|
Matthew T.G. Holden
Erin P. Price
Sharon J. Peacock
Wellcome Trust Sanger Institute
Menzies School of Health Research
University of Cambridge
University of St Andrews, School of Medicine
|Citation:||Journal of Clinical Microbiology. Vol.52, No.9 (2014), 3418-3421|
|Abstract:||We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei after inoculation and systemic spread. Copyright © 2014 Limmathurotsakul et al.|
|Appears in Collections:||Scopus 2011-2015|
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