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Title: Dialysis dose and risk factors for death among ESRD patients treated with twice-weekly hemodialysis: A prospective cohort study
Authors: Thanachai Panaput
Bandit Thinkhamrop
Somnuek Domrongkitchaiporn
Dhavee Sirivongs
Laksamon Praderm
Jirasak Anukulanantachai
Chavasak Kanokkantapong
Pakorn Tungkasereerak
Cholatip Pongskul
Sirirat Anutrakulchai
Thathsalang Keobounma
Surapong Narenpitak
Pisith Intarawongchot
Ammrit Suwattanasin
Sajja Tatiyanupanwong
Kannika Niwattayakul
Khon Kaen University
Mahidol University
Khon Kaen Regional Hospital
Roi-Et Hospital
Maharaj Nakhon Ratchasima Hospital
Surin Hospital
Thabo Crown Prince Hospital
Nong Khai Hospital
Udon Thani Center Hospital
Mahasarakham Hospital
Chaiyapoom Hospital
Muang Loei Ram Hospital
Keywords: Medicine
Issue Date: 1-Jan-2014
Citation: Blood Purification. Vol.38, No.3-4 (2014), 253-262
Abstract: © 2015 S. Karger AG, Basel. Background/Aims: We aimed to define the dosing and risk factors for death in patients undergoing twice-weekly hemodialysis. Methods: A prospective multi-center cohort study was conducted with one-year observation. Patients treated with twice- or thrice-weekly hemodialysis were identified. Death and first admission were the outcomes. spKt/V was a factor of interest. Results: We enrolled 504 twice-weekly and 169 thrice-weekly hemodialysis patients. The mean weekly values of spKt/V in the two groups were 3.4 and 5.1. The one-year survival rate and times to hospitalization were similar in both groups. The hazard ratios for death in higher spKt/V quartile was not associated with lower mortality, p = 0.70. The four significant predictors for death were serum albumin, HR = 2.6, current smoking, HR = 19.3, age, HR = 1.1, and the Index of Coexistent Disease [ICED], HR = 1.9. Conclusion: The effect of spKt/V on short-term mortality was not obvious in twice-weekly dialysis patients. Attention should be paid to patients who smoke, have hypoalbuminemia, are elderly, or have a high ICED.
ISSN: 14219735
Appears in Collections:Scopus 2011-2015

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