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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/34873
Title: Current information and asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: Systematic review and practice recommendations from an early nutrition academy workshop
Authors: Berthold Koletzko
Christopher C.M. Boey
Cristina Campoy
Susan E. Carlson
Namsoo Chang
Maria Antonia Guillermo-Tuazon
Sadhana Joshi
Christine Prell
Seng Hock Quak
Damayanti Rusli Sjarif
Yixiang Su
Sarayut Supapannachart
Yuichiro Yamashiro
Saskia J.M. Osendarp
Klinikum der Universitat Munchen
University of Malaya
Universidad de Granada
University of Kansas Medical Center
Ewha Womans University
University of the Philippines Los Banos
Bharati Vidyapeeth University
National University Hospital, Singapore
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
Mahidol University
Juntendo University School of Medicine
Osendarp Nutrition
The Micronutrient Initiative
Sun Yat-Sen University
Keywords: Medicine;Nursing
Issue Date: 1-Jan-2014
Citation: Annals of Nutrition and Metabolism. Vol.65, No.1 (2014), 49-80
Abstract: © 2014 S. Karger AG, Basel. The Early Nutrition Academy supported a systematic review of human studies on the roles of pre- and postnatal longchain polyunsaturated fatty acids (LC-PUFA) published from 2008 to 2013 and an expert workshop that reviewed the information and developed recommendations, considering particularly Asian populations. An increased supply of n-3 LC-PUFA during pregnancy reduces the risk of preterm birth before 34 weeks of gestation. Pregnant women should achieve an additional supply ≥ 200 mg docosahexaenic acid (DHA)/day, usually achieving a total intake ≥ 300 mg DHA/day. Higher intakes (600-800 mg DHA/day) may provide greater protection against early preterm birth. Some studies indicate beneficial effects of pre- and postnatal DHA supply on child neurodevelopment and allergy risk. Breast-feeding is the best choice for infants. Breast-feeding women should get ≥ 200 mg DHA/day to achieve a human milk DHA content of ∼ 0.3% fatty acids. Infant formula for term infants should contain DHA and arachidonic acid (AA) to provide 100 mg DHA/day and 140 mg AA/day. A supply of 100 mg DHA/day should continue during the second half of infancy. We do not provide quantitative advice on AA levels in follow-on formula fed after the introduction of complimentary feeding due to a lack of sufficient data and considerable variation in the AA amounts provided by complimentary foods. Reasonable intakes for very-low-birth weight infants are 18-60 mg/ kg/day DHA and 18-45 mg/kg/day AA, while higher intakes (55-60 mg/kg/day DHA, ∼ 1% fatty acids; 35-45 mg/kg/day AA, ∼0.6-0.75%) appear preferable. Research on the requirements and effects of LC-PUFA during pregnancy, lactation, and early childhood should continue.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84908562442&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/34873
ISSN: 14219697
02506807
Appears in Collections:Scopus 2011-2015

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