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|Title:||Antimycobacterial dihydronaphthalenone from the endophytic fungus Nodulisporium sp. of Antidesma ghaesembilla|
|Keywords:||Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology|
|Citation:||Phytochemistry Letters. Vol.13, (2015), 375-378|
|Abstract:||© 2015 Elsevier Ltd. Abstract Two new dihydronaphthalenones (1, 2) with four known compounds (3-6) were isolated as secondary metabolites of the endophytic fungus Nodulisporium sp. from Antidesma ghaesembilla. Their chemical structures were established based on 1D and 2D NMR spectroscopic data and HR-ESI-MS analyses. The relative configuration of 2 was confirmed by single crystal X-ray crystallographic analysis. A new isofuranonaphthalenone 2 displayed antimycobacterial and antimalarial activities with IC<inf>50</inf> values of 3.125 and 11.3 μg/mL, respectively.|
|Appears in Collections:||Scopus 2011-2015|
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