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|Title:||Recent trends in rapid environmental monitoring of pathogens and toxicants: Potential of nanoparticle-based biosensor and applications|
Jong Il Weon
Faculty of Environment and Resource Studies, Mahidol University
Dongguk University, Seoul
King Mongkuts University of Technology Thonburi
|Keywords:||Biochemistry, Genetics and Molecular Biology;Environmental Science|
|Citation:||Scientific World Journal. Vol.2015, (2015)|
|Abstract:||© 2015 Preeyaporn Koedrith et al. Of global concern, environmental pollution adversely affects human health and socioeconomic development. The presence of environmental contaminants, especially bacterial, viral, and parasitic pathogens and their toxins as well as chemical substances, poses serious public health concerns. Nanoparticle-based biosensors are considered as potential tools for rapid, specific, and highly sensitive detection of the analyte of interest (both biotic and abiotic contaminants). In particular, there are several limitations of conventional detection methods for water-borne pathogens due to low concentrations and interference with various enzymatic inhibitors in the environmental samples. The increase of cells to detection levels requires long incubation time. This review describes current state of biosensor nanotechnology, the advantage over conventional detection methods, and the challenges due to testing of environmental samples. The major approach is to use nanoparticles as signal reporter to increase output rather than spending time to increase cell concentrations. Trends in future development of novel detection devices and their advantages over other environmental monitoring methodologies are also discussed.|
|Appears in Collections:||Scopus 2011-2015|
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