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Title: ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA<inf>2</inf>
Authors: A. D. Stephens
R. Colah
S. Fucharoen
J. Hoyer
D. Keren
A. Mcfarlane
D. Perrett
B. J. Wild
Institute of Immunohaematology Mumbai
Mahidol University
Mayo Clinic
University of Michigan, Ann Arbor
Institute for Quality Management in Healthcare (IQMH)
Barts and The London School of Medicine Charterhouse Square
Hammersmith Hospital
Keywords: Biochemistry, Genetics and Molecular Biology
Issue Date: 1-Jan-2015
Citation: International Journal of Laboratory Hematology. Vol.37, No.5 (2015), 577-582
Abstract: © 2015 John Wiley & Sons Ltd. Automated high performance liquid chromatography and Capillary electrophoresis are used to quantitate the proportion of Hemoglobin A<inf>2</inf> (HbA<inf>2</inf>) in blood samples order to enable screening and diagnosis of carriers of β-thalassemia. Since there is only a very small difference in HbA<inf>2</inf> levels between people who are carriers and people who are not carriers such analyses need to be both precise and accurate. This paper examines the different parameters of such equipment and discusses how they should be assessed.
ISSN: 1751553X
Appears in Collections:Scopus 2011-2015

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