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dc.contributor.authorSabine Dittrichen_US
dc.contributor.authorPiyanate Sunyakumthornen_US
dc.contributor.authorSayaphet Rattanavongen_US
dc.contributor.authorRattanaphone Phetsouvanhen_US
dc.contributor.authorPhonepasith Panyanivongen_US
dc.contributor.authorAmphonsavanh Sengduangphachanhen_US
dc.contributor.authorPhonelavanh Phouminhen_US
dc.contributor.authorTippawan Anantataten_US
dc.contributor.authorAnisone Chanthongthipen_US
dc.contributor.authorSue J. Leeen_US
dc.contributor.authorAudrey Dubot-Péresen_US
dc.contributor.authorNicholas P.J. Dayen_US
dc.contributor.authorDaniel H. Parisen_US
dc.contributor.authorPaul N. Newtonen_US
dc.contributor.authorGareth D.H. Turneren_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUniversity of Oxforden_US
dc.date.accessioned2018-11-23T10:20:13Z-
dc.date.available2018-11-23T10:20:13Z-
dc.date.issued2015-01-01en_US
dc.identifier.citationAmerican Journal of Tropical Medicine and Hygiene. Vol.93, No.2 (2015), 232-237en_US
dc.identifier.issn00029637en_US
dc.identifier.other2-s2.0-84939244128en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84939244128&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/36148-
dc.description.abstract© 2015 by The American Society of Tropical Medicine and Hygiene. Blood-brain barrier (BBB) function and cerebrospinal fluid (CSF) biomarkers were measured in patients admitted to hospital with severe neurological infections in the Lao People's Democratic Republic (N = 66), including bacterial meningitis (BM; N = 9) or tuberculosis meningitis (TBM; N = 11), Japanese encephalitis virus (JEV; N = 25), and rickettsial infections (N = 21) including murine and scrub typhus patients. The albumin index (AI) and glial fibrillary acidic protein (GFAP) levels were significantly higher in BM and TBM than other diseases but were also raised in individual rickettsial patients. Total tau protein was significantly raised in the CSF of JEV patients. No differences were found between clinical or neurological symptoms, AI, or biomarker levels that allowed distinction between severe neurological involvement by Orientia tsutsugamushi compared with Rickettsia species.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84939244128&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleBlood-brain barrier function and biomarkers of central nervous system injury in rickettsial versus other neurological infections in Laosen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.4269/ajtmh.15-0119en_US
Appears in Collections:Scopus 2011-2015

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