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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/36152
Title: Antimicrobial disk susceptibility testing of leptospira spp. Using leptospira vanaporn wuthiekanun (LVW) agar
Authors: Vanaporn Wuthiekanun
Premjit Amornchai
Sayan Langla
Nicholas J. White
Nicholas P.J. Day
Direk Limmathurotsakul
Sharon J. Peacock
Mahidol University
University of Oxford
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jan-2015
Citation: American Journal of Tropical Medicine and Hygiene. Vol.93, No.2 (2015), 241-243
Abstract: © 2015 by The American Society of Tropical Medicine and Hygiene. Leptospira Vanaporn Wuthiekanun (LVW) agar was used to develop a disk diffusion assay for Leptospira spp. Ten pathogenic Leptospira isolates were tested, all of which were susceptible to 17 antimicrobial agents (amoxicillin/ clavulanic acid, amoxicillin, azithromycin, cefoxitin, ceftazidime, ceftriaxone, chloramphenicol, ciprofloxacin, clindamycin, doripenem, doxycycline, gentamicin, linezolid, nitrofurantoin, penicillin, piperacillin/tazobactam, and tetracycline). All 10 isolates had no zone of growth inhibition for four antimicrobials (fosfomycin, nalidixic acid, rifampicin, and trimethoprim/ sulfamethoxazole). Of the ten Leptospira, seven had a growth inhibition zone of 21 mm for aztreonam, the zone diameter susceptibility break point for Enterobacteriaceae. This assay could find utility as a simple screening method during the epidemiological surveillance of antimicrobial resistance in Leptospira spp.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84939223945&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/36152
ISSN: 00029637
Appears in Collections:Scopus 2011-2015

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