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dc.contributor.authorNattawat Onlamoonen_US
dc.contributor.authorVajee Petphongen_US
dc.contributor.authorKasama Sukapiromen_US
dc.contributor.authorSiyu Wangen_US
dc.contributor.authorPalanee Ammaranonden_US
dc.contributor.authorKovit Pattanapanyasaten_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherChulalongkorn Universityen_US
dc.date.accessioned2018-11-23T10:20:48Z-
dc.date.available2018-11-23T10:20:48Z-
dc.date.issued2015-01-01en_US
dc.identifier.citationImmunotherapy. Vol.7, No.7 (2015), 765-775en_US
dc.identifier.issn17507448en_US
dc.identifier.issn1750743Xen_US
dc.identifier.other2-s2.0-84942108152en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84942108152&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/36157-
dc.description.abstract© 2015 Future Medicine Ltd. Aims: CD4+ T lymphocytes from HIV-infected patients with different degrees of disease progression based on CD4 count were expanded in vitro using anti-CD3/28-coated beads. Materials & methods: Purified CD4+ T lymphocytes from healthy subjects and patients were expanded for 3 weeks. Moreover, the improvement of cell expansion by IL-2 supplementation was also determined. Results: Expanded CD4+ T lymphocytes from patients had lower fold expansion when compared with healthy subjects. Furthermore, patients with high CD4 counts had higher fold expansion than patients with low CD4 count, and IL-2 supplementation further increased cell expansion. Conclusions: Anti-CD3/28 activation failed to potently induce expansion of CD4+ T lymphocytes from patients. However, the cell expansion could be improved by IL-2 supplementation.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84942108152&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.titleProduction of anti-CD3/28 expanded CD4<sup>+</sup> T lymphocytes from HIV-infected patients with different degrees of disease progressionen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.2217/imt.15.41en_US
Appears in Collections:Scopus 2011-2015

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