Simple jQuery Dropdowns
Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorNattawat Onlamoonen_US
dc.contributor.authorVajee Petphongen_US
dc.contributor.authorKasama Sukapiromen_US
dc.contributor.authorSiyu Wangen_US
dc.contributor.authorPalanee Ammaranonden_US
dc.contributor.authorKovit Pattanapanyasaten_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherChulalongkorn Universityen_US
dc.identifier.citationImmunotherapy. Vol.7, No.7 (2015), 765-775en_US
dc.description.abstract© 2015 Future Medicine Ltd. Aims: CD4+ T lymphocytes from HIV-infected patients with different degrees of disease progression based on CD4 count were expanded in vitro using anti-CD3/28-coated beads. Materials & methods: Purified CD4+ T lymphocytes from healthy subjects and patients were expanded for 3 weeks. Moreover, the improvement of cell expansion by IL-2 supplementation was also determined. Results: Expanded CD4+ T lymphocytes from patients had lower fold expansion when compared with healthy subjects. Furthermore, patients with high CD4 counts had higher fold expansion than patients with low CD4 count, and IL-2 supplementation further increased cell expansion. Conclusions: Anti-CD3/28 activation failed to potently induce expansion of CD4+ T lymphocytes from patients. However, the cell expansion could be improved by IL-2 supplementation.en_US
dc.rightsMahidol Universityen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleProduction of anti-CD3/28 expanded CD4<sup>+</sup> T lymphocytes from HIV-infected patients with different degrees of disease progressionen_US
Appears in Collections:Scopus 2011-2015

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.