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|Title:||Consequences of circadian disruption on cardiometabolic health|
Kristen L. Knutson
University of Chicago
|Citation:||Sleep Medicine Clinics. Vol.10, No.4 (2015), 455-468|
|Abstract:||© 2015 Elsevier Inc. Cardiovascular disease, diabetes and obesity are highly prevalent diseases associated with reduced quality of life and life expectancy. We discuss a novel risk factor for these cardiometabolic diseases: circadian disruption. Circadian disruption occurs when the internal circadian (∼24-hour) rhythms are not in synchrony with the environment or each other. This paper reviews (1) cardiometabolic health of shift work, which often leads to circadian disruption, (2) effects of experimentally disrupted circadian rhythms on cardiometabolic function, (3) observational studies of sleep timing and behavioral chronotype, and (4) potential mediators linking chronotype and shift work to circadian disruption and cardiometabolic health.|
|Appears in Collections:||Scopus 2011-2015|
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