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Title: Reticulate hyperpigmentation in systemic sclerosis: A case report and review of the literature
Authors: Mati Chuamanochan
Andrea L. Haws
Penvadee Pattanaprichakul
Mahidol University
University of Texas Health Science Center at Houston
Keywords: Medicine
Issue Date: 28-Sep-2015
Citation: Journal of Medical Case Reports. Vol.9, No.1 (2015)
Abstract: © 2015 Chuamanochan et al. Introduction: Systemic sclerosis is a systemic connective tissue disease with variable cutaneous presentations. Although pigmentary disturbances have been described in systemic sclerosis, a reticulate hyperpigmentation has only been reported in one case of systemic sclerosis to date. Case presentation: We describe a previously healthy 51-year-old Thai woman who presented with a reticulate hyperpigmentation affecting her trunk and extremities, together with sclerodactyly and proximal sclerosis, resulting in a new diagnosis of systemic sclerosis. Conclusions: To date, the pathogenesis of reticulate hyperpigmentation in systemic sclerosis remains unclear. Increased melanin synthesis and altered thermoregulatory mechanism are proposed to be involved in the pathogenesis of this presentation. This case represents an unusual cutaneous feature of reticulate hyperpigmentation in the setting of systemic sclerosis.
ISSN: 17521947
Appears in Collections:Scopus 2011-2015

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