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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/36406
Title: Periodontal disease in patients with chronic coronary heart disease: Prevalence and association with cardiovascular risk factors
Authors: Ola Vedin
Emil Hagström
Dianne Gallup
Megan L. Neely
Ralph Stewart
Wolfgang Koenig
Andrzej Budaj
Piyamitr Sritara
Lars Wallentin
Harvey D. White
Claes Held
Akademiska Sjukhuset
Duke Clinical Research Institute
Auckland City Hospital
Universitat Ulm
Szpital Grochowski, Warszawa
Mahidol University
Keywords: Medicine
Issue Date: 11-Jun-2015
Citation: European Journal of Preventive Cardiology. Vol.22, No.6 (2015), 771-778
Abstract: © 2014 The European Society of Cardiology. Aim: There are reported links between periodontal disease (PD) and cardiovascular (CV) risk but data are lacking, especially from populations with established coronary heart disease (CHD). This study describes self-reported indicators of PD and associations with CV risk factors in a global stable CHD population. Methods and results: A total of 15,828 participants in the global STABILITY trial underwent a physical examination, blood sampling, and completed a lifestyle questionnaire. They reported remaining number of teeth (none, 1-14, 15-20, 21-25 or 26-32 (all)) and frequency of gum bleeding (never/rarely, sometimes, often or always). Adjusted linear and logistic regression models assessed associations between tooth loss, gum bleeding, and socioeconomic and CV risk factors. A total of 40.9% of participants had <15 remaining teeth; 16.4% had no teeth; and 25.6% reported gum bleeding with large differences in prevalence among countries, regions and ethnic groups. Less tooth loss was associated with lower levels of glucose, low-density lipoprotein (LDL) cholesterol, systolic blood pressure, waist circumference and hs-CRP; higher estimated glomerular filtration rate; decreased odds for diabetes and smoking, and increased odds for higher education, alcohol consumption and work stress. Gum bleeding was associated with higher LDL cholesterol and systolic blood pressure; decreased odds for smoking, but increased odds for higher education, alcohol consumption and stress. Conclusion: Self-reported indicators of PD were common in this chronic CHD population and were associated with an increasing socioeconomic and CV risk factor burden. However, causality between self-reported PD and CV risk and outcome needs further investigation.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84929090682&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/36406
ISSN: 20474881
20474873
Appears in Collections:Scopus 2011-2015

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