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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/36430
Title: Comorbidities frequency in takotsubo syndrome: An international collaborative systematic review including 1109 patients
Authors: Francesco Pelliccia
Guido Parodi
Cesare Greco
David Antoniucci
Roman Brenner
Eduardo Bossone
Luca Cacciotti
Alessandro Capucci
Rodolfo Citro
Clément Delmas
Federico Guerra
Costin N. Ionescu
Olivier Lairez
Maiteder Larrauri-Reyes
Pil Hyung Lee
Nicolas Mansencal
Giuseppe Marazzi
Christos G. Mihos
Olivier Morel
Holger M. Nef
Ivan J. Nunez Gil
Ilaria Passaseo
Andres M. Pineda
Giuseppe Rosano
Orlando Santana
Franziska Schneck
Bong Gun Song
Jae Kwan Song
Andrew W. Teh
Patompong Ungprasert
Alberto Valbusa
Andreas Wahl
Tetsuro Yoshida
Carlo Gaudio
Juan Carlos Kaski
Universita degli Studi di Roma La Sapienza
Azienda Ospedaliera Careggi
Kantonsspital Olten
University Hospital San Giovanni di Dio e Ruggi d'Aragona
Ospedale Madre G. Vannini
Universita Politecnica delle Marche
Hopital de Rangueil
Yale University
Mount Sinai Medical Center Miami Beach
University of Ulsan, College of Medicine
Universite de Versailles Saint-Quentin-en-Yvelines
IRCCS San Raffaele Pisana
Pôle d'Activité Medico-chirurgicale Cardiovasculaire
Justus Liebig University Giessen
Hospital Clinico San Carlos de Madrid
St George's University of London
Konkuk University Hospital
Monash University
Austin Hospital
Mahidol University
IRCCS Istituto Giannina Gaslini - Ospedale Pediatrico
UniversitatsSpital Bern
Onga Hospital
Keywords: Medicine
Issue Date: 1-Jun-2015
Citation: American Journal of Medicine. Vol.128, No.6 (2015), 654.e11-654.e19
Abstract: © 2015 Elsevier Inc. All rights reserved. Background To identify predisposing factors that can result in the onset of takotsubo syndrome, we performed an international, collaborative systematic review focusing on clinical characteristics and comorbidities of patients with takotsubo syndrome. Methods We searched and reviewed cited references up to August 2013 to identify relevant studies. Corresponding authors of selected studies were contacted and asked to provide additional quantitative details. Data from each study were extracted by 2 independent reviewers. The cumulative prevalence of presenting features and comorbidities was assessed. Nineteen studies whose authors sent the requested information were included in the systematic review, with a total of 1109 patients (951 women; mean age, 59-76 years). Evaluation of risk factors showed that obesity was present in 17% of patients (range, 2%-48%), hypertension in 54% (range, 27%-83%), dyslipidemia in 32% (range, 7%-59%), diabetes in 17% (range, 4%-34%), and smoking in 22% (range, 6%-49%). Emotional stressors preceded takotsubo syndrome in 39% of patients and physical stressors in 35%. The most common comorbidities were psychological disorders (24%; range, 0-49%), pulmonary diseases (15%; range, 0-22%), and malignancies (10%; range, 4%-29%). Other common associated disorders were neurologic diseases (7%; range, 0-22%), chronic kidney disease (7%; range, 2%-27%), and thyroid diseases (6%; range, 0-37%). Conclusions Patients with takotsubo syndrome have a relevant prevalence of cardiovascular risk factors and associated comorbidities. Such of associations needs to be evaluated in further studies.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84930384373&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/36430
ISSN: 15557162
00029343
Appears in Collections:Scopus 2011-2015

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