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dc.contributor.authorJitsupa Wongsripuemteten_US
dc.contributor.authorOragarn Wongfukiaten_US
dc.contributor.authorYudthaphon Vichianinen_US
dc.contributor.authorChanon Ngamsombaten_US
dc.contributor.authorTheerapol Witthiwejen_US
dc.contributor.authorBunpot Sitthinamsuwanen_US
dc.contributor.authorThaweesak Aurboonyawaten_US
dc.contributor.authorEkawut Chankaewen_US
dc.contributor.authorOrasa Chawalpariten_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-12-11T03:14:44Z
dc.date.accessioned2019-03-14T08:01:53Z-
dc.date.available2018-12-11T03:14:44Z
dc.date.available2019-03-14T08:01:53Z-
dc.date.issued2016-12-01en_US
dc.identifier.citationJournal of the Medical Association of Thailand. Vol.99, No.12 (2016), 1344-1354en_US
dc.identifier.issn01252208en_US
dc.identifier.other2-s2.0-85015396230en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85015396230&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/40953-
dc.description.abstract© 2016, Medical Association of Thailand. All rights reserved. Objective: To evaluate the concordance of language lateralization between functional magnetic resonance imaging (fMRI) using Thai version of language paradigm and Wada test or awake surgery with direct cortical brain stimulation (DCS). Material and Method: Retrospective study of thirteen patients (3 males and 10 females with mean age of 33.9 years old) with epilepsy (7 cases) or brain tumor (6 cases) was performed. Every patient underwent both fMRI (word generation, verb generation, naming picture, and sentence completion tasks) and Wada test or awake surgery with DCS (defined as the gold standard). The lateralization index (LI) of fMRI was automatically calculated by using the LI-toolbox on SPM8. The hemispheric lateralization was also evaluated visually. The concordance between fMRI and gold standard were analyzed. Results: The concordance between the lateralization of fMRI by visual assessment and gold standard was 92.3%. Concordance between the calculated LI by fMRI and gold standard was varied along with the task and regional calculation method. The concordance was good in all tasks (except for naming picture task) when using calculated LI from frontal or whole brain excluded cerebellum and occipital lobe (range 76.92 to 88.98% and 76.92 to 92.31%, respectively). Conclusion: There was good concordance between fMRI and gold standard. Regional calculation from frontal lobes and whole brain excluded cerebellum and occipital lobes gave the best results. The results supported feasibility to use the fMRI with Thai language paradigm as an alternative way to determine the language dominant hemisphere in Thai patients. In case of language dominant hemisphere is unclear, further invasive investigation of language mapping such as Wada test or DCS is crucial.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85015396230&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleFeasibility study of language lateralization using thai version of language paradigm for functional MRI in clinical serviceen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
Appears in Collections:Scopus 2016-2017

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