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Title: Comparison of the efficacy and safety of 0.1% tacrolimus ointment and 0.1% mometasone furoate cream for adult vitiligo: A single-blinded pilot study
Authors: Narumol Silpa-Archa
Sunatra Nitayavardhana
Kanchalit Thanomkitti
Leena Chularojanamontri
Supenya Varothai
Chanisada Wongpraparut
Mahidol University
Keywords: Medicine
Issue Date: 1-Dec-2016
Citation: Dermatologica Sinica. Vol.34, No.4 (2016), 177-179
Abstract: © 2016 Topical tacrolimus has demonstrated efficacy in vitiligo. This study compared the efficacy and safety of 0.1% tacrolimus ointment with 0.1% mometasone furoate cream in adult vitiligo. We enrolled patients with symmetrical, nonacral vitiligo, and the patients on each side were randomized to receive either 0.1% tacrolimus ointment or 0.1% mometasone furoate cream, applied twice daily for 6 months. Repigmentation outcome at 6 months was compared with baseline. Of 18 cases, 22% and 33% in tacrolimus and mometasone groups, respectively, displayed more than 50% repigmentation (p > 0.05). Telangiectasia was presented in one-third of cases on the mometasone-treated side. Both treatments were effective in vitiligo; however, 0.1% tacrolimus ointment has fewer adverse effects.
ISSN: 2223330X
Appears in Collections:Scopus 2016-2017

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