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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/41028
Title: Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report
Authors: Vilasinee Rerkpichaisuth
Jennifer A. Collins
Thiraphon Boonyaarunnate
Syed Z. Ali
Mahidol University
The Johns Hopkins School of Medicine
Keywords: Medicine
Issue Date: 1-Nov-2016
Citation: Diagnostic Cytopathology. Vol.44, No.11 (2016), 917-920
Abstract: © 2016 Wiley Periodicals, Inc. Well-differentiated fetal adenocarcinoma (WDFA) of the lung is a rare variant of adenocarcinoma with an unusual morphology. Although the histologic features of this rare neoplasm have been well established, there is a deficit in the literature with regards to its discrete cytomorphologic features. We report the fine needle aspiration (FNA) findings of a case of this unusual malignancy in a 44-year-old man with an incidental lung nodule. FNA revealed three-dimensional clusters of epithelial cells with scant cytoplasm, hyperchromatic nuclei that are associated with an extracellular metachromatic matrix. The original cytology report was signed out as an epithelial neoplasm favor adenoid cystic carcinoma. Consequently, a wedge resection of the lung was done and the histologic diagnosis was WDFA of the lung. The findings of minimal nuclear atypia in association with focally abundant spheres of extracellular matrix can mimic adenoid cystic carcinoma. WDFA has good prognosis and therefore, pre-operative cytologic diagnosis is critical to clinical management. We present the cytomorphologic features of this neoplasm with particular emphasis on a potential diagnostic pitfall of this rare entity. Diagn. Cytopathol. 2016;44:917–920. © 2016 Wiley Periodicals, Inc.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978164213&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/41028
ISSN: 10970339
87551039
Appears in Collections:Scopus 2016-2017

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